Love scripting in PHP? Want to use it to create full-fledged windowed applications and not just flat web sites? PHP-GTK allows you to do just that by binding Gtk+, the object-oriented windowing system that makes GIMP’s interface work, to PHP code. Just install PHP (no web server necessary for this type of development) and add the PHP-GTK extension to it like you would any other extension. It is fairly straightforward. The draw I find with this is that you can create PHP code (more-or-less designed for handling web information) with a window (by far a more user-intuitive object). More information about the extension can be found on their web site.

http://gtk.php.net/faq.php